Effect of intra-abdominal instillation of lidocaine during minor laparoscopic procedures.

Author(s): El-Sherbiny W, Saber W, Askalany AN, El-Daly A, Sleem AA

Affiliation(s): Department of Obstetrics and Gynecology, Cairo University Faculty of Medicine, Cairo, Egypt. wssherbiny@yahoo.com

Publication date & source: 2009-09, Int J Gynaecol Obstet., 106(3):213-5. Epub 2009 May 27.

OBJECTIVE: To assess the effect of intraperitoneal instillation of lidocaine on postoperative pain after minor gynecological laparoscopic surgery. METHOD: A prospective, double-blind, placebo-controlled clinical trial of 75 patients undergoing gynecological laparoscopy randomized to receive intraperitoneal instillation of either 120 mg of lidocaine (n=60) or normal saline (n=15) at the end of surgery. Postoperative pain was evaluated by Wong-Baker Faces Pain Rating Scale (WBFS) score at 15 minutes and at 1, 2, 4, 12, and 24 hours postoperatively. RESULTS: The WBFS score was lower for the lidocaine group than for the control group at 1, 2, and 4 hours after surgery (P=0.023). There was no difference in WBFS scores between the 2 groups at 15 minutes (P=0.46), 12 hours (P=0.13), and 24 hours (P=0.07) after surgery. CONCLUSION: Intraperitoneal instillation of lidocaine was effective in reducing postoperative pain after minor gynecological laparoscopic procedures.