The effect of twice daily nadolol on intraocular pressure.

Author(s): Duff GR

Affiliation(s): Department of Ophthalmology, University Hospital of Wales, Cardiff, U.K.

Publication date & source: 1987-10-15, Am J Ophthalmol., 104(4):343-5.

Publication type: Clinical Trial; Randomized Controlled Trial

The 12-hour control of intraocular pressure obtained with 10 and 20 mg of nadolol twice daily was studied in a placebo-controlled trial. In this ten-week study involving 17 patients a significant reduction in intraocular pressure was obtained with both doses. The effect of 20 mg of nadolol twice daily on intraocular pressure, resting pulse rate, and blood pressure was consistently slightly greater than 10 mg twice daily, but the difference was not significant.