The dangers of dextropropoxyphene.

Author(s): Dore GM

Affiliation(s): Dunedin School of Medicine, University of Otago, New Zealand.

Publication date & source: 1996-12, Aust N Z J Psychiatry., 30(6):864-6.

Publication type: Case Reports

OBJECTIVE: Dextropropoxyphene is a commonly used analgesic despite its high toxicity in overdose and potential for abuse and dependence. This case report highlights these dangers. CLINICAL PICTURE: The case of a female who was addicted to dextropropoxyphene as an alternative to other opioids is described. Its use in high doses with other psychotropic agents resulted in adverse health effects. TREATMENT: The patient was treated with methadone and psychosocial interventions. OUTCOME: The patient reduced her drug use and experienced improved physical health and psychosocial functioning. CONCLUSIONS: Caution is needed when prescribing dextropropoxyphene because of its adverse effects compared with equally efficacious analgesics.