A randomized trial of microdose leuprolide acetate protocol versus luteal phase ganirelix protocol in predicted poor responders.

Author(s): DiLuigi AJ, Engmann L, Schmidt DW, Benadiva CA, Nulsen JC

Affiliation(s): Center for Advanced Reproductive Services, University of Connecticut Heath Center, Farmington, Connecticut 06030-6224, USA. diluigi@uchc.edu

Publication date & source: 2011-06-30, Fertil Steril., 95(8):2531-3. Epub 2011 Feb 16.

Publication type: Comparative Study; Randomized Controlled Trial

We performed a randomized trial to compare IVF outcomes in 54 poor responder patients undergoing a microdose leuprolide acetate (LA) protocol or a GnRH antagonist protocol incorporating a luteal phase E(2) patch and GnRH antagonist in the preceding menstrual cycle. Cancellation rates, number of oocytes retrieved, clinical pregnancy rates (PR), and ongoing PRs were similar between the two groups. Copyright (c) 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.