Single-day praziquantel versus 1-week albendazole for neurocysticercosis.

Author(s): Del Brutto OH, Campos X, Sanchez J, Mosquera A

Affiliation(s): Department of Neurology, Luis Vernaza Hospital, Guayaquil, Ecuador.

Publication date & source: 1999-03-23, Neurology., 52(5):1079-81.

Publication type: Clinical Trial; Randomized Controlled Trial

The efficacy of albendazole (15 mg/kg/d for 1 week) was compared with praziquantel (100 mg/kg in three divided doses at 2-hour intervals) for therapy of parenchymal brain cysticercosis. Ten patients were treated with albendazole and 10 patients with praziquantel. Although the total number of cysts was significantly reduced from 64 to 7 in patients treated with albendazole and from 59 to 24 in those treated with praziquantel, the number of patients improving with albendazole was not significantly different from those treated with praziquantel.