Double-blind comparison of zopiclone and flunitrazepam in elderly insomniacs with special focus on residual effects.

Author(s): Dehlin O, Rubin B, Rundgren A

Affiliation(s): Department of Internal Medicine, University Hospital, Lund, Sweden.

Publication date & source: 1995, Curr Med Res Opin., 13(6):317-24.

Publication type: Clinical Trial; Comparative Study; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

In a double-blind study of 102 patients with a mean age of 79 years, zopiclone was compared to flunitrazepam. The patients rated their sleep in a diary. There was no statistically significant difference between the relatively low dose of 5 mg zopiclone and 1 mg flunitrazepam for eleven out of the twelve variables measuring subjective sleep quality and quantity. There was no differences between the drugs as regards patients' feelings of being rested or alertness.