Intubation conditions and postoperative myalgia in outpatient dental surgery: a
comparison of succinylcholine with mivacurium.
Author(s): Deehan S, Henderson D, Stewart K.
Affiliation(s): Department of Anaesthetics, St John's Hospital at Howden, Livingston, West
Lothian, U.K.
Publication date & source: 2000, Anaesth Intensive Care. , 28(2):146-50
Ninety-four patients undergoing elective outpatient third molar extraction were
recruited into a double-blind, randomized, prospective trial comparing mivacurium
(group M) with succinylcholine (Group S) for conditions for endotracheal
intubation and the occurrence of postoperative myalgia. Anaesthesia was induced
with fentanyl 1 microgram.kg-1 and propofol 2.5 micrograms.kg-1 in all patients.
Group S patients were given gallamine 20 mg while group M patients were given
mivacurium 0.2 mg.kg-1. Manual ventilation was commenced and anaesthesia
maintained with nitrous oxide 70% and isoflurane 1 to 2% in oxygen. After two
minutes, group S patients were given succinylcholine 1.5 mg.kg-1 and group M
patients 0.9% saline. Nasotracheal intubation was performed 30 seconds later.
Intubating conditions in group M were significantly better than those in group S
(P < 0.001). The incidence of postoperative myalgia was 9.5% in group M and 26%
in group S but this was not statistically significant (P = 0.09). We propose that
mivacurium is a suitable neuromuscular blocker to use for endotracheal intubation
in outpatient dental surgery.
|