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Association of chlorhexidine and fluoride for plaque control and white spot lesion remineralization in primary dentition.

Author(s): de Amorim RG, Leal SC, Bezerra AC, de Amorim FP, de Toledo OA

Affiliation(s): Department of Paediatric Dentistry, School of Health Sciences, University of Brasilia, Brasilia, Brazil.

Publication date & source: 2008-11, Int J Paediatr Dent., 18(6):446-51. Epub 2008 May 16.

Publication type: Randomized Controlled Trial

BACKGROUND: Plaque control and caries arrest still remain a challenge for dentists. OBJECTIVE: This study was conducted to assess the effect of the combined use of chlorhexidine varnish and fluoride varnish on the visible plaque index (VPI) and white spot lesion (WS) remineralization in primary dentition. METHODS: A total of 80 caries-active preschool children (3-5 years) were randomly divided into four groups. Group 1 received a chlorhexidine varnish application every week during 4 weeks. Group 2 received a fluoride varnish application every week during 4 weeks. Group 3 received alternated applications of chlorhexidine and fluoride varnish during 4 weeks. Group 4 served as control (without any type of cariostatic agent). RESULTS: There was no statistically significant difference in the VPI and WS remineralization among the groups after 1 month. However, 3 months follow-up demonstrated that group 3 (chlorhexidine + fluoride) showed significantly better results for both VPI and WS remineralization. CONCLUSION: The combined application of chlorhexidine and fluoride varnishes is more effective on plaque and remineralization of incipient caries after 3 months than the same agents applied separately.

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