Pregnancy after avascular necrosis of the femur complicating Gaucher's disease.

Author(s): Cleary JE, Burke WM, Baxi LV

Affiliation(s): Department of Obstetrics and Gynecology, Sloane Hospital for Women at the New York Presbyterian Hospital, College of Physicians and Surgeons at Columbia University, New York, New York, USA.

Publication date & source: 2001-01, Am J Obstet Gynecol., 184(2):233-4.

Publication type: Case Reports

A patient with type I Gaucher's disease had avascular necrosis of the right femoral head that resulted in an altered bony pelvis and marked restriction of right hip abduction. Enzyme replacement therapy with alglucerase prevented further deterioration and improved thrombocytopenia. Vaginal delivery was achieved with the patient in the left lateral position with exaggerated flexion at the contralateral hip.