Oxcarbazepine use in paroxysmal kinesigenic dyskinesia: report on four patients.

Author(s): Chillag KL, Deroos ST

Affiliation(s): Department of Pediatric Neurology, Helen DeVos Children's Hospital, Grand Rapids, Michigan, USA. kipp.chillag@devoschildrens.org

Publication date & source: 2009-04, Pediatr Neurol., 40(4):295-7.

Publication type: Case Reports

The paroxysmal dyskinesias are a heterogeneous group of movement disorders. They are distinguished from one another by the mechanism through which abnormal movements are induced. Paroxysmal kinesigenic dyskinesia is the most common subtype, consisting of involuntary dyskinesias induced by purposeful movements. It typically responds favorably to anticonvulsants. This retrospective review describes four unrelated children and adolescents with idiopathic paroxysmal kinesigenic dyskinesia who were treated with oxcarbazepine. Each patient achieved complete resolution of signs with low-dose oxcarbazepine monotherapy.