Cystic changes in hepatic metastases from gastrointestinal stromal tumors (GISTs) treated with Gleevec (imatinib mesylate).
Author(s): Chen MY, Bechtold RE, Savage PD
Affiliation(s): Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157-1088, USA.
Publication date & source: 2002-10, AJR Am J Roentgenol., 179(4):1059-62.
Publication type: Clinical Trial; Randomized Controlled Trial
OBJECTIVE: The purpose of this article is to illustrate the CT findings in patients with hepatic metastases from a gastrointestinal stromal tumor who were treated with STI-571. CONCLUSION: Hepatic metastases from gastrointestinal stromal tumors that respond to treatment with STI-571 can appear as near-cystic components with well-defined borders on contrast-enhanced CT. Most metastases became smaller. These metastases resemble simple cysts, but density measurements may differentiate them from one another.
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