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Prilocaine versus lignocaine for minor lid procedures.

Author(s): Burton AJ, Backhouse O, Metcalfe TW

Affiliation(s): Leeds General Infirmary, UK. tony.355@virginnet.co.uk

Publication date & source: 2000-08, Eye., 14 ( Pt 4):594-6.

Publication type: Clinical Trial; Randomized Controlled Trial

PURPOSE: To determine whether prilocaine is a more comfortable local infiltration anaesthetic agent than the more widely used lignocaine for minor eyelid procedures. METHODS: A prospective randomised study was undertaken to compare the discomfort between local infiltration of plain 2% prilocaine versus its equivalent, plain 2% lignocaine. One hundred and twenty-five patients were recruited. Pain was assessed subjectively using a visual analogue pain score, graded from 0 to 10. RESULTS: The mean pain score for the prilocaine group was 1.82 compared with 3.19 for the lignocaine group. Using the Mann-Whitney U-test for significance, U = 1236.5; p < 0.001. CONCLUSION: Prilocaine is a more comfortable local infiltration anaesthetic agent than lignocaine when used for minor eyelid procedures.

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