[Hemolytic anemia in a newborn after maternal treatment with nitrofurantoin at the end of pregnancy]

Author(s): Bruel H, Guillemant V, Saladin-Thiron C, Chabrolle JP, Lahary A, Poinsot J

Affiliation(s): Service de medecine neonatale, hopital Flaubert, Le Havre, France.

Publication date & source: 2000-07, Arch Pediatr., 7(7):745-7.

Publication type: Case Reports; English Abstract

Drug administration during the last trimester of pregnancy may have adverse effects for the newborn. CASE REPORT: A hemolytic anemia occurred during the first hours of life in a full-term neonate whose mother had taken nitrofurantoin during the last month of pregnancy. CONCLUSION: The immature enzymatic systems of the neonate are exposed to this adverse effect and justify the recommendation not to prescribe nitrofurantoin at the end of pregnancy.