Hodgkin's disease: the Milan Cancer Institute experience with MOPP and ABVD.
Author(s): Bonadonna G, Valagussa P, Santoro A, Viviani S, Bonfante V, Banfi A
Affiliation(s): Divisions of Medical Oncology, Istituto Nazionale Tumori, Milan, Italy.
Publication date & source: 1989, Recent Results Cancer Res., 117:169-74.
Publication type: Clinical Trial; Randomized Controlled Trial
The report includes the essential therapeutic and toxic results following MOPP vs. MOPP/ABVD and MOPP vs. ABVD within a combined modality setting. The findings indicate that in stage IV the alternating regimen is superior to MOPP while in stage IIB-III ABVD plus radiotherapy yielded superior results associated with no treatment-induced sterility and leukemia compared with MOPP plus radiotherapy.
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