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Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial.

Author(s): Blanke CH, Naisabha GB, Balema MB, Mbaruku GM, Heide L, Muller MS

Affiliation(s): Matyazo Health Centre, Diocese of Western Tanganyika, Kigoma, Tanzania. christophblanke@yahoo.com

Publication date & source: 2008-04, Trop Doct., 38(2):113-6.

Publication type: Comparative Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Tea preparations from the herb Artemisia annua L. (Aa) which is used in traditional Chinese medicine might offer an inexpensive way of producing artemisinin drugs locally. We compared Aa with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated falciparum malaria in semi-immune adults. After seven days, the cure rate was 7/10 for the Aa compared to 7/9 for SP; this dropped to 4/10 for Aa and 4/9 for SP at day 14 and to 1/9 for Aa and 3/8 for SP at day 28.

Page last updated: 2008-08-11

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