Postpneumonic empyema in childhood.
Author(s): Belet N, Uysal S, Bernay E, Gurses N
Affiliation(s): Department of Pediatrics, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey.
Publication date & source: 2001-01, Indian J Pediatr., 68(1):11-4.
Publication type: Clinical Trial; Randomized Controlled Trial
Fifty-six patients with postpneumonic empyema were treated by sulbactam/ampicillin or cephalothin and netilmicin. Dose of sulbactam/ampicillin was 200 mg/kg per day and of cephalothin was 200 mg/kg per day, and of netilmicin was 5 mg/kg per day. Sulbactam/ampicillin alone was used in 27 patients. Twenty-nine patients were treated with cephalothin plus netilmicin. Days on intravenous antibiotics, days with chest tube, decortication rate, and duration of hospitalization were significantly shorter in sulbactam/ampicillin treatment group compared to cephalothin plus netilmicin group. This study shows that sulbactam/ampicillin is a safe and effective agent in the treatment of postpneumonic empyema in childhood.
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