Case of corneal melting associated with the use of topical nepafenac.
Author(s): Bekendam PD, Narvaez J, Agarwal M
Affiliation(s): Department of Ophthalmology, Loma Linda University Medical Center, Loma Linda, CA, USA.
Publication date & source: 2007-09, Cornea., 26(8):1002-3.
Publication type: Case Reports
PURPOSE: To report a case of corneal melting associated with the use of the topical nonsteroidal anti-inflammatory agent Nepafenac. METHODS: Case report and literature review. RESULTS: A 62-year-old woman with a complicated ocular history developed corneal melting associated with the use of Nepafenac. On discontinuation of Nepafenac, the melt rapidly resolved. CONCLUSIONS: Topical nonsteroidal anti-inflammatory agents have been associated with corneal ulceration and stromal melts. This is, to our knowledge, the first reported case involving the new agent, Nepafenac.
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