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Trimethoprim-polymyxin B sulphate ophthalmic ointment in the treatment of bacterial conjunctivitis: a double-blind study versus chloramphenicol ophthalmic ointment.

Author(s): Behrens-Baumann W, Quentin CD, Gibson JR, Calthrop JG, Harvey SG, Booth K

Affiliation(s): Augenklinik and Poliklinik, Georg-August-Universitat, Gottingen, West Germany.

Publication date & source: 1988, Curr Med Res Opin., 11(4):227-31.

Publication type: Clinical Trial; Randomized Controlled Trial

Forty-two patients with a clinical diagnosis of bacterial conjunctivitis were enrolled in a randomized, double-blind trial. Patients were treated with either trimethoprim-polymyxin B sulphate or chloramphenicol ophthalmic ointments 4-times a day for 7 days. Analysis of clinical evaluation data showed that both treatments were effective and well tolerated, and that there were no statistically significant differences between them with regard to eradication of organisms or clinical improvement.

Page last updated: 2006-01-31

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