A comparative study of Norinyl 1/35 versus Norinyl 1/50 in Belgrade, Yugoslavia.

Author(s): Behilovic B, Rowan AJ

Affiliation(s): Faculty of Medicine, Dom Zdravlja Stari Grad, Belgrade, Yugoslavia.

Publication date & source: 1987-11, Contraception., 36(5):515-26.

Publication type: Clinical Trial; Randomized Controlled Trial

A comparative study of Norinyl 1/35 and Norinyl 1/50 was conducted at the Dom Zdravlja Stari Grad in Belgrade, Yugoslavia. The study sought to evaluate the differences in continuation rates as well as the frequency of selected side effects which might contribute to method discontinuation. The trial included 299 women who were randomly allocated to one of the two oral contraceptives. In the Norinyl 1/35 group, significantly more women (p less than .05) reported a complaint of vaginal discharge as well as an increase in the occurrence of vaginal discharge compared to the Norinyl 1/50 group. There was no significant difference in continuation rates or for particular discontinuation reasons for the Norinyl 1/35 and Norinyl 1/50 groups. No accidental pregnancies were reported during this study. Both oral contraceptives appear to be safe and effective; there appears to be no difference in the acceptability of one oral contraceptive over the other among this group of Yugoslavian women.