Resolution of an oral ulcer secondary to acetaminophen/hydrocodone withdrawal.

Author(s): Balasubramaniam R, Lin PC, White DK, Yepes JF

Affiliation(s): Orofacial Pain Center, College of Dentistry and Medicine, University of Kentucky, Lexington, USA.

Publication date & source: 2007-09, Gen Dent., 55(5):441-4.

Publication type: Case Reports

Acetaminophen/hydrocodone is a common non-opioid/opioid analgesic indicated for the treatment of moderate to severe pain. The following report depicts a unique case involving a 57-year-old woman with a persistent, painful oral ulcer that was unresponsive to standard treatments. The ulcer was resolved when the patient discontinued acetaminophen/hydrocodone use. The cause of the ulcer is unclear but it was speculated to result from a systemic hypersensitivity reaction to acetaminophen/hydrocodone.