Field trial of praziquantel for control of fishborne zoonotic trematodes in reservoir hosts in Vietnam.
Author(s): Anh NT, Madsen H, Thanh DT, Dalsgaard A, Murrell KD
Affiliation(s): National Institute of Veterinary Research, 86 Truong Chinh, Hanoi, Viet Nam. email@example.com
Publication date & source: 2010-12-15, Vet Parasitol., 174(3-4):348-50. Epub 2010 Sep 29.
Publication type: Randomized Controlled Trial; Research Support, Non-U.S. Gov't
This field trial was conducted to determine whether 40 or 75 mg/kg of praziquantel is suitable for treatment of fishborne zoonotic trematodes (FZT) in naturally infected dogs (n=10) and cats (n=11). Three days after treatment all animals at either dose were negative for small trematode eggs. In two cats and one dog treated with 75 mg/kg, however, a few damaged eggs were found 3 days post-treatment; no small trematode eggs were seen in these animals at day 14 post-treatment. In addition, at the 75 mg dose, two cats and two dogs experienced vomiting or diminished appetite. Therefore a praziquantel dose of 40 mg/kg is suggested for treatment of FZT in dogs and cats. Copyright (c) 2010 Elsevier B.V. All rights reserved.