Renal hypersensitivity vasculitis associated with dapsone.
Author(s): Alves-Rodrigues EN, Ribeiro LC, Silva MD, Takiuchi A, Rabel-Filho OC, Martini-Filho D, Fontes CJ
Affiliation(s): Departamento de Clinica Medica, Hospital Universitario Julio Muller, Universidade Federal de Mato Grosso, Cuiaba, Brazil.
Publication date & source: 2005-10, Am J Kidney Dis., 46(4):e51-3.
Publication type: Case Reports
We describe clinical and pathological features of kidney and skin involvement in a patient with hypersensitivity vasculitis associated with dapsone. Although visceral damage occurs rarely, similar skin and kidney histopathologic and immunohistochemical findings indicate that this organ is a target for type IV cell-mediated dapsone reaction. To our knowledge, this is the first reported case of renal hypersensitivity vasculitis associated with dapsone.
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