Resolution of nocturnal enuresis in snoring children after treatment with nasal budesonide.

Author(s): Alexopoulos EI, Kaditis AG, Kostadima E, Gourgoulianis K

Affiliation(s): Department of Pediatrics, University of Thessaly School of Medicine and Larissa University Hospital, Larissa, Greece. ealexop@yahoo.com

Publication date & source: 2005-07, Urology., 66(1):194.

Publication type: Case Reports

Nocturnal enuresis has been associated with obstructive sleep apnea-hypopnea and may resolve after adenotonsillectomy. Nasal corticosteroids have improved symptoms and polysomnography findings in children with snoring. Two children with primary nocturnal enuresis, chronic nasal obstruction, and loud snoring underwent polysomnography. The apnea-hypopnea index was 4.9 and 7.3 episodes/hr, and the oxygen desaturation of hemoglobin index was 4.6 and 5.2 episodes/hr. After administration of budesonide, the frequency of snoring decreased, the polysomnography findings improved, and the enuresis resolved completely. Six months after treatment, both children were still dry at night. Administration of nasal corticosteroids is associated with resolution of enuresis in children with mild obstructive sleep-disordered breathing.