Rapid sequence induction and intubation with 1 mg/kg rocuronium bromide in cesarean section, comparison with suxamethonium.

Author(s): Abu-Halaweh SA, Massad IM, Abu-Ali HM, Badran IZ, Barazangi BA, Ramsay MA

Affiliation(s): Department of General Surgery, Anesthesia and Intensive Care, College of Medicine, University of Jordan, PO Box 13046, Amman 11942, Jordan. sami_halaweh@yahoo.com

Publication date & source: 2007-09, Saudi Med J., 28(9):1393-6.

Publication type: Randomized Controlled Trial

OBJECTIVE: To demonstrate that Rocuronium Bromide can be used for rapid sequence induction in emergency conditions. METHODS: Our study was performed between December 2005 and May 2006 in Jordan University Hospital, Jordan. We studied the efficacy and intubating conditions after administrating of Rocuronium Bromide 1 mg/kg at 60 second in group of 60 pregnant women undergoing elective or emergency cesarean section and compared the results with those obtained after giving Suxamethonium 1 mg/kg at 60 seconds in a group of patients similar to the Rocuronium group. RESULTS: Intubating conditions after 1 mg /kg of Rocuronium Bromide were found to be acceptable (good and excellent) in 95% of patients and were similar to the Suxamethonium group (97%). The endotracheal tube could be passed through the vocal cards of all patients enrolled in the study. CONCLUSION: Rocuronium Bromide 1 mg/kg can be safely used for rapid sequence induction in cesarean section and the intubating conditions are similar to those of Suxamethonium.